Publications

Manuscripts

2023

  1. Giles JB, Rollin J, Martinez KL, Selleng K, Thiele T, Pouplard C, Sheppard JI, Heddle NM, Phillips EJ, Roden DM, Gruel Y, Warkentin TE, Greinacher A, Karnes JH. Laboratory and Demographic Predictors of Functional Assay Positive Status in Suspected Heparin-Induced Thrombocytopenia: A Multicenter Retrospective Cohort Study. Thromb Res. 2023 [In Press]

2022

  1. Steiner HE, Carrion KC, Giles JB, Lima AR, Yee K, Sun X, Cavallari LH, Perera MA, Duconge J, Karnes JH. Local Ancestry-Informed Candidate Pathway Analysis of Warfarin Stable Dose in Latino Populations. Clin Pharmacol Ther. 2022 Nov 2. PMID: 36321873.

  2. Steiner HE, Patterson HK, Giles JB, Karnes JH. Bringing pharmacomicrobiomics to the clinic through well-designed studies. Clin Transl Sci. 2022 Oct;15(10):2303-2315 Epub 2022 Aug 9. PMID: 35899413

  3. Giles JB, Steiner HE, Rollin J, Shaffer CM, Momozawa Y, Mushiroda T, Inai C, Selleng K, Thiele T, Pouplard C, Heddle NM, Kubo M, Miller EC, Martinez KL, Phillips EJ, Warkentin TE, Gruel Y, Greinacher A, Roden DM, Karnes JH. Genome-wide association study of platelet factor 4/heparin antibodies in heparin-induced thrombocytopenia. Blood Adv. 2022 Jul 26;6(14):4137-4146. PMID: 35533259

  4. Karnes JH, Rollin J, Giles JB, Martinez KL, Steiner HE, Shaffer CM, Momozawa Y, Inai C, Bombin A, Shi M, Mosley JD, Stanaway I, Selleng K, Thiele T, Mushiroda T, Pouplard C, Heddle NM, Kubo M, Phillips EJ, Warkentin TE, Gruel Y, Greinacher A, Roden DM. ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia. Blood. 2022 Jul 21;140(3):274-284. PMID: 35377938

  5. Morningstar-Kywi N, Wang K, Asbell TR, Wang Z, Giles JB, Lai J, Brill D, Sutch BT, Haworth IS. Prediction of Water Distributions and Displacement at Protein-Ligand Interfaces. J Chem Inf Model. 2022 Mar 28;62(6):1489-1497. Epub 2022 Mar 9. PMID: 35261241.

  6. Miller E, Norwood C, Giles JB, Huddart R, Karnes JH, Whirl-Carrillo M, Klein TE. PharmGKB summary: heparin-induced thrombocytopenia pathway, adverse drug reaction. Pharmacogenet Genomics. 2022 Jan 31. Epub ahead of print. PMID: 35102073.

  7. Giles JB, Miller EC, Steiner HE, Karnes JH. Elucidation of Cellular Contributions to Heparin-Induced Thrombocytopenia Using Omic Approaches. Front Pharmacol. 2022 Jan 21; 12:812830. PMID: 35126147

2021

  1. Steiner HE, Gee K, Giles JB, Knight H, Hurwitz BL, Karnes JH. Role of the gut microbiome in cardiovascular drug response: The potential for clinical application. Pharmacotherapy. 2021 Nov 25. Epub ahead of print. PMID: 34820870.

  2. Steiner HE, Giles JB, Patterson HK, Feng J, El Rouby N, Claudio K, Marcatto LR, Tavares LC, Galvez JM, Calderon-Ospina CA, Sun X, Hutz MH, Scott SA, Cavallari LH, Fonseca-Mendoza DJ, Duconge J, Botton MR, Santos PCJL, Karnes JH. Machine Learning for Prediction of Stable Warfarin Dose in US Latinos and Latin Americans. Front Pharmacol. 2021 Oct 29; 12:749786. PMID: 34776967

  3. Deshpande P, Hertzman RJ, Palubinsky AM, Giles JB, Karnes JH, Gibson A, Phillips EJ. Immunopharmacogenomics: Mechanisms of HLA-Associated Drug Reactions. Clin Pharmacol Ther. 2021 Sep;110(3):607-615. Epub 2021 Jul 17. PMID: 34143437

2020

  1. Karnes JH, Weiner HW, Schwantes-An T, Natarajan B, Sweatt AJ, Chaturvedi A, Arora A, Batai K, Nair V, Steiner HE, Giles JB, Yu J, Hosseini M, Pauciulo MW, Lutz KA, Coleman AW, Feldman J, Vanderpool R, Tang H, Garcia JGN, Yuan JXJ, Kittles R, Perez VDJ, Zamanian RT, Rischard F, Tiwari HK, Nichols WC, Benza RL, Desai AA. Genetic admixture and survival in diverse populations with pulmonary arterial hypertension. Am J Respir Crit Care Med. 2020. PMID: 31916850

2019

  1. Dab Brill, Giles JB, Ian S. Haworth, Aiichiro Nakano: WaterAlignment: Identification of displaced water molecules in molecular docking using Jonker and Volgenant shortest path augmentation for linear assignmentBlissful-days-please! . Comput. Phys. Commun. 244: 324-328 (2019). https://doi.org/10.1016/j.cpc.2019.06.021

Book Chapters

  1. Jason B. Giles, Dab A. Brill, Alexis Chavoya, Ian S. Haworth. Algorithms for the Predictions of Peptides Binding to Major Histocompatibility Complex (MHC) Molecules [Book Chapter]. Advances in Chemistry Research Volume 46. ISBN: 978-1-53614-216-7. August 2018.

Abstracts

  1. Giles JB, Kiana L Martinez, Jo-Ann Sheppard, Kayla Lucier, Jerome Rollin, Kathleen Selleng, Thomas Thiele, Claire Pouplard, Yves Gruel, Andreas Greinacher, Nancy M Heddle, Dan M Roden, Theodore E Warkentin, Jason H Karnes (2023) Lack of Association Between Abo Blood Groups and Rhesus Antigen with Heparin-Induced Thrombocytopenia. Pharmacogenomics Research Network Annual Meeting (PGRN), Memphis, TN. June 2023.

  2. Steiner, H., El Rouby, N., Claudio, K., Rodrigues Marccatto, L., Giles JB., Rodrigues Botton, M., Scott, S., Cavallari, L., Duconge, J., Caleb De Lima Santos, P., Karnes, J. (2021) “(Pt21-012) Validity of International Warfarin Pharmacogenetics Consortium (Iwpc) Dosing Algorithm and Application of Machine Learning to Predict Warfarin Dose Variability In Us Latino And Latin American Populations.” American Society of Clinical Pharmacology and Therapeutics Annual Meeting. Virtual. Mar. 2021.

  3. Knight, H., Steiner, H.E., Giles, J.B., Heise, W., Karnes, J.H. Potential for Dietary Vitamin K Intake to Predict Variability in Weekly Warfarin Dose. 6th Annual Arizona Biomedical Research Centre (ABRC)- Flinn Research Conference (Virtual), February 2021.

  4. Giles JB, Jérôme Rollin, Christian M Shaffer, Heidi E Steiner, Yukihide Momozawa, Ian Stanaway, Taisei Mushiroda, Claire Pouplard, Nancy Heddle, Michiaki Kubo, Elizabeth Phillips, Theodore E. Warkentin, Yves Gruel, Andreas Greinacher, Dan Roden, Jason Karnes; Genome-Wide Association Study Identifies Variation in ABO As Risk Factor for Platelet Reactivity in Heparin-Induced Thrombocytopenia. Blood 2020; 136 (Supplement 1): 38–39.

  5. Steiner HE, Giles JB, Knight H, Fox K, Stanaway IB, Heise W, Karnes JH. Association of the ABO O Blood Group with Increased Warfarin Stable Dose. Pharmacogenomics Research Network Annual Meeting, October 2020.

  6. Karnes, J. H., Wiener, H., Schwantes-An, T.-H., Natarajan, B., Chaturvedi, A., Arora, A. H., Batai, K., Nair V., Steiner, H.E., Giles JB, Desai, A. (2019). Abstract 10124: Genetic Admixture and Survival in Diverse Populations with Pulmonary Arterial Hypertension (PAH). American Heart Association Scientific Sessions, Philadelphia, PA, Nov 2019.

  7. Gutierrez L, Giles JB, Jang M, Akhtari M, Haworth I, Alachkar H; Development of T Cell Receptor Analysis Based Strategy to Identify Leukemia Specific Neoantigens. Adoptive Immunotherapy. Blood 2018; 132 (Supplement 1): 4549.